Stem Cell Program Leadership

George Q. Daley, MD, PhD

George Q. Daley, MD, PhD
Samuel E. Lux Professor of Hematology
Director, Stem Cell Transplantation Program
Children's Hospital Boston
Professor of Biological Chemistry and Molecular Pharmacology and Pediatrics
Harvard Medical School
Investigator, Howard Hughes Medical Institute

George Q. Daley is internationally recognized as an expert in stem cell research and for his work in chronic myeloid leukemia (CML), a cancer of the blood caused by genetically defective stem cells. His current research is aimed at translating insights in stem cell biology into cellular therapies for degenerative, malignant and genetic diseases.

Dr. Daley’s laboratory reported the first successful application of somatic cell nuclear transfer to generate customized embryonic stem cells to treat genetic disease in a mouse model of immune deficiency (together with Rudolf Jaenisch) and the first creation of functional sperm cells from embryonic stem cells, work that was cited by Science magazine as a “Top Ten” breakthrough for 2003. More recently, Science magazine cited Dr. Daley’s creation of disease-specific stem cells from patients in its 2008 Breakthrough of the Year issue.

While serving as a laboratory principal investigator at Boston Children’s Hospital, Dr. Daley is Dean and Caroline Shields Walker Professor of Medicine, and Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. Prior to becoming Dean he was the Robert A. Stranahan Professor of Pediatrics and director of the Pediatric Stem Cell Transplantation Program at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and a Howard Hughes Medical Institute investigator. Dr. Daley received a PhD in Biology from MIT, working with Nobelist Dr. David Baltimore, and his MD from Harvard Medical School, where he was only the twelfth individual in the school’s history to be awarded the degree summa cum laude. Daley pursued clinical training in internal medicine at Massachusetts General Hospital, where he served as chief resident (1994-1995), and a clinical fellowship in hematology/oncology at Brigham and Women’s Hospital and Children’s. He was a founding executive committee member of the Harvard Stem Cell Institute, served as president of the International Society for Stem Cell Research (2007-2008), and anchored the special task forces that produced the society’s guidelines for stem cell research and clinical translation (2006, 2008, 2016). Daley has been elected to the National Academy of Medicine, the American Society for Clinical Investigation, the American Association of Physicians, the American Pediatric Societies, the American Academy of Arts and Sciences and the American Association for the Advancement of Science. He was an inaugural winner of the NIH Director’s Pioneer Award, and has won the E. Donnall Thomas Prize of the American Society of Hematology.

Read more about Dr. Daley’s work:

Giving

Spotlight

  • Blood diseases: The First Frontier

    Hematologist George Q. Daley, MD, PhD, Director of Stem Cell Transplantation
    Program, has seen children with blood diseases die, often because they aren’t candidates for bone marrow transplants, currently the best tool for treating many of these diseases. Daley hopes to employ pluripotent stem cells to create safer, genetically matched bone-marrow transplants for patients. Read more.